JIAHUI HEALTH
An International Healthcare Ecosystem
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Hospital Profile

Jiahui International Cancer Center is affiliated to Shanghai Jiahui International Hospital and is a strategic cooperative medical center in China with Massachusetts General Hospital and its cancer center. It is led by a number of clinical leaders who represent the forefront of international cancer diagnosis and treatment, providing patients over the age of 14 years with rapid, international-standard cancer diagnosis and treatment services. Jiahui International Cancer Center supports direct payment from more than 50 global mainstream insurance companies and is connected to the Chinese Basic Medical Insurance in order to provide convenient payment options. Services: Anti-tumor drug treatment (chemotherapy, targeted, immune), tumor radiation therapy, tumor surgical treatment, tumor complication management, cancer pain management, palliative care, tumor nutrition, rehabilitation physical therapy, psychological counseling, PICC/PORT insertion and maintenance, HAIC/TACE interventional treatment, etc. Tumor types: Digestive tract tumors (liver cancer, bile duct cancer, stomach cancer, colorectal cancer, pancreatic cancer, esophageal cancer, etc.), breast cancer, lung cancer, urinary system tumors (bladder cancer, prostate cancer, kidney cancer, adrenal gland tumors, etc.), Gynecological tumors (cervical cancer, endometrial cancer, ovarian cancer, etc.), head and neck tumors (nasopharyngeal cancer, laryngeal cancer, thyroid cancer), hematological tumors (lymphoma, bone marrow cancer, leukemia, etc.), other tumors (sarcoma, thyroid cancer, melanoma, brain tumors, etc.)

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Car-T Therapy

Shanghai Jiahui International Cancer Center (JICC) CAR-T is led by Dr. Vicky H. Lee (Directorof JICC), an internationally renowned hematologist. JICC provides CAR-T-related diagnosisand treatment services integrating international partner hospitals such as MassachusettsGeneral Hospital in the United States, as well as leveraging local high-quality medicalresources in Shanghai, such as Ruijin Hospital and Tongji Hospital. The services includeoutpatient consultation, screening and evaluation, T-cell collection, CAR-T infusion, sideeffects monitoring and management, etc.Shanghai Jiahui International Hospital has developed a standard service process and qualitycontrol system based on the international CAR-T clinical guidelines, ensuring the customizedtreatment of patients. Additionally, the CAR-T rapid response team has been established, witha multidisciplinary clinical professional team consisting of department heads from the CancerCenter, Neurology, Cardiology, Respiratory Medicine, ICU, Laboratory, Pharmacy, and otherdepartments. Multiple rounds of clinical training and scenario simulations have beenconducted in the early stages to ensure the full process management of CAR-T treatment.Advanced CAR-T extraction equipment and CAR-T special wards have been set up. Bothhardware and software fully guarantee patient monitoring needs and a comfortable experience.Shanghai Jiahui International Cancer Center (JICC) has completed multiple CAR-T trainingcertifications, including FosunKite Bio and IASO Bio, and has been authorized for treatmentcertification, enabling the initiation of clinical applications of CAR-T cell immunotherapy.

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CAR-T cooperative network system
Hospital level/expert level cooperation network with domestic tertiary hospitals and top international medical institutions for hematology diagnosis and treatment services
Pro-active exploration of patient support options through the innovative payment model of CAR-T with partners including Fosun Kate and IASO Biology. JICC aims to build an international CAR-T treatment service and academic exchange platform at Shanghai Jiahui International Hospital.
Highly personalized treatment plan and environment
Dedicated CAR-T ward to fully ensure the needs of patient monitoring and care
Strict adherence to privacy protection and ability to accommodate patients from different cultural backgrounds from China and overseas
A patient-centered treatment plan will be assessed and conducted to achieve the "golden opportunity" for patients. CAR-T and related preparation treatments are arranged in a timely manner.
CAR-T Treatment Advantages at Jiahui International Cancer Center
At JICC we are committed to maximizing: Treatment Effectiveness + Patient Safety + Experience
International standards throughout the entire treatment process:
Led by a director who has CAR-T clinical practice experience in the United States, a CAR-T rapid response team with capabilities to manage CAR-T adverse reactions/complications has been established
Multidisciplinary team discussions will be arranged for each case to maximize the patient's treatment benefits
Standardized clinical service processes and quality control system based on the international CAR-T clinical guidelines in place.
Introduction of experts
Vicky LEE
    Director, Jiahui International Cancer Center, MD
  • Member of Beijing Medical University (BMU)
  • Member of the Washington State Medical Oncology Society (WSMOS)
  • Member of the American Society of Clinical Oncology (ASCO)
  • Member of the American Society of Hematology (ASH)
  • Member of the Oregon Society of Medical Oncology (OSMO)
  • Dr. [Name] holds an MD from Beijing Medical University (BMU) and has worked at BMU Hospital for three years. She later pursued cancer immunology research at the prestigious Kyoto University School of Medicine in Japan, followed by breast cancer research at New York University School of Medicine in the United States. During her time in the U.S., she achieved board certifications in Internal Medicine, Hematology, and Oncology from the American Board of Internal Medicine (ABIM). In 2018, she received a certificate in Cancer Genetic Risk Assessment from City of Hope. She is licensed to practice medicine in Oregon and Washington State and is internationally renowned in cancer treatment, hematology, and cancer risk assessment.

Case Study
Foreign patient successfully received CAR-T treatment at Shanghai Jiahui International Hospital
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Fucaso® (Equecabtagene Autoleucel Injection)

-- The World's First Approved Fully Human CAR-T Therapy

Breakthrough fully human CAR structure
  • Full epitope of light and heavy chains binds tightly to BCMA
  • Fast dissociation, low exhaustion
  • Low immunogenicity
Durable persistence
  • Median duration of persistence time 419 days
  • 12-month sustained MRD negativity rate 81.7%
  • 12-month PFS rate 85.5%
Strong efficacy
  • ORR 98.9%
  • ≥CR rate 82.4%
  • MRD negativity rate 97.8%
Returning to life upon single-dose treatment
Excellent safety
  • No ≥ Grade 3 ICANS
  • Incidence of ≥ Grade 3
  • No movement/cognitive disorder observed No Parkinson's disease found