GOBROAD MEDICAL
(HEMATOLOGY) SHANGHAI
RESEARCH CENTER
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Hospital Profile

Basic and clinical studies on multiple myeloma have been focused since the Gaobo Medical Group entered Shanghai in 2019, establishing the Gaobo Medical (Hematology) Shanghai Research Center. It operates two hematology hospitals: Shanghai Zhaxin Hospital in Jing'an District and Shanghai Liquan Hospital in Fengxian District. Both hospitals are comprehensive facilities specializing in the diagnosis and treatment of hematological diseases. They cover a total construction area of 18,000 square meters and offer over 300 beds, including 32 hematopoietic stem cell transplant laminar flow wards. The hospitals are equipped with imported MRI and CT machines and feature departments such as medical laboratories, blood banks, medical imaging, and pharmacy. They are members of the Shanghai Ruijin Hematology Medical Consortium.

In addition to routine clinical testing, the hospitals can conduct specialized laboratory tests related to hematological diseases, such as cell morphology, flow cytometry, chromosome and fluorescence in situ hybridization (FISH), gene testing, and PCR testing.

The Gaobo Medical (Hematology) Shanghai Research Center integrates medical treatment, teaching, and research. It utilizes a comprehensive diagnostic system and the most advanced chemical and biomedical technologies to diagnose and treat hematological and immunological diseases. The center is dedicated to becoming the most influential hematology specialty hospital in East China, leveraging the high-level medical team’s expertise to enhance the international influence of its hematology department. Both Zhaxin and Liquan Hospitals provide a warm and comfortable environment, are designated institutions for Shanghai medical insurance, and have implemented nationwide real-time medical insurance settlement, greatly meeting patients' medical needs.

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Introduction to the Hematology Department
The Gaobo Medical (Hematology) Shanghai Research Center is led by Professor Wang Chun, former Director of the Hematology Department at Shanghai First People’s Hospital. Professor Wang has over 40 years of experience in the field of hematological disease diagnosis and treatment. He is highly experienced in hematopoietic stem cell transplantation for refractory leukemia, especially in elderly patients, as well as in the management of infections in hematological diseases. His expertise is widely recognized and praised in both domestic and international academic circles. The core members of the medical and technical team also come from Shanghai First People’s Hospital and possess extensive practical experience in the diagnosis, treatment, and care of various hematological diseases.
Specialty Features
  • Precision diagnosis and treatment of malignant hematological diseases
  • Transplant therapy for elderly leukemia patients
  • Salvage therapy for refractory leukemia
  • T-cell lymphoma
  • Salvage therapy for relapsed/refractory lymphoma
  • Immunosuppressive therapy for severe aplastic anemia
  • Treatment of primary myelofibrosis
  • Salvage therapy for myelodysplastic syndromes
  • Post-transplant management of allogeneic hematopoietic stem cell transplantation
  • Sequential autologous and allogeneic transplantation for multiple myeloma
Department Environment

The Hematology Department offers a warm and comfortable medical environment, equipped with state-of-the-art medical facilities. It is capable of diagnosing and treating various types of hematological diseases. The department specializes in integrated diagnosis and personalized treatment of hematological disorders, with expertise in selecting and formulating comprehensive treatment plans and strategies for hematologic malignancies, including chemotherapy, targeted therapy, and radiotherapy. Additionally, the medical team places great emphasis on medication safety. They adjust drug dosages based on the patient's pharmacogenetics and drug concentration monitoring to ensure the safety and effectiveness of treatments.

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Expert Introduction
Wang Chun

    Professor Wang Chun is a Chief Physician and the academic leader and Medical Director at the GaoBo Medical (Hematology) Shanghai Research Center. He previously served as the Director of the Hematology Department at Shanghai First People's Hospital and as a PhD supervisor at the same institution affiliated with Shanghai Jiao Tong University. His primary research focuses on hematopoietic stem cell transplantation and the prevention and treatment of infections in hematology.

    Professor Wang holds numerous prestigious positions, including Chairman of the Ninth Hematology Branch of the Shanghai Medical Association, Deputy Chairman of the Shanghai Medical Association's Infection and Chemotherapy Committee, Vice President of the First Hematology Branch of the Shanghai Medical Association, Committee Member of the Bacteriology and Antimicrobial Resistance Branch of the Chinese Medical Association, Member and Secretary-General of the Eighth Hematology Branch of the Chinese Medical Association, Deputy Leader of the Infection Group, Executive Member of the Hematological Oncology Professional Committee of the Chinese Anti-Cancer Association, Member of the Hematology Branch of the Chinese Medical Association, and Editorial Board Member of several Chinese medical journals.

    He has published over 100 professional papers in renowned domestic and international journals, including 25 articles in the Science Citation Index (SCI). In 2001, Professor Wang was interviewed by the British journal "The Lancet Oncology." His academic papers, published in top SCI journals such as the "Journal of Clinical Oncology," "Clinical Infectious Diseases," and "Blood Cancer Journal," cover topics like strategies for preventing and treating fungal and bacterial infections in hematological patients, mechanisms of antithymocyte globulin-induced leukemia cell killing, applications of high-dose etoposide in hematopoietic stem cell mobilization, hematopoietic stem cell transplantation for T-cell lymphoma, post-transplant immunosuppressant adjustment strategies, monitoring of donor-recipient chimerism after allogeneic hematopoietic stem cell transplantation, and graft-versus-host disease (GVHD) monitoring.

    Professor Wang's work on "The Establishment and Clinical Application of Key Technologies for Salvage Treatment of Refractory Malignant Hematological Diseases by Allogeneic Hematopoietic Stem Cell Transplantation" won the Second Prize of the Chinese Medical Science and Technology Award in 2017. His project on "The Establishment of a System for Salvage Treatment of Refractory Malignant Hematological Diseases by Allogeneic Hematopoietic Stem Cell Transplantation" won the Second Prize of the Excellent Achievement Award in Scientific Research (Science and Technology) of Higher Education Institutions by the Ministry of Education in 2016. Professor Wang was also awarded the "Renxin Yizhe·Shanghai Outstanding Specialist Physician Award" in 2016.

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Wang Chun
    Associate Chief Physician and Medical Director
  • Member of the Hematology Institution Branch of the Chinese Hospital Association
  • Member of the District and County Coordination Group of the Hematology Branch of the Shanghai Medical Association
  • Young Editorial Board Member of the Chinese edition of "BLOOD"
  • Formerly employed in the Hematology Department of the First People's Hospital, he has 20 years of professional experience in the diagnosis and treatment of hematological diseases. His primary focus is on hematopoietic stem cell transplantation and the prevention and treatment of infections in patients with febrile neutropenia. He has published papers in the journal "Clinical Infectious Diseases" (CID).

    Expertise:
  • Diagnosis and treatment of various hematological diseases
  • Management of patients post-hematopoietic stem cell transplantation
  • Salvage treatment of peripheral T-cell lymphoma through allogeneic hematopoietic stem cell transplantation
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Chuxian Zhao
    Associate Chief Physician, MD
  • Member of the Leukemia Collaboration Group of the Hematology Branch of the Shanghai Medical Association.
  • Former Attending Physician in the Hematology Department at Shanghai First People's Hospital, with nearly 20 years of professional experience in diagnosing and treating hematological diseases.
  • Has published multiple articles in the "Chinese Medical Journal" and the "Chinese Journal of Hematology."
  • Participated in a major project by the Shanghai Science and Technology Committee: a multicenter study on the refined diagnosis, classification, and standardized treatment of acute leukemia.
  • Expertise:
  • Diagnosis and treatment of acute and chronic leukemia, aplastic anemia, and other hematological diseases.
  • Management of patients post-hematopoietic stem cell transplantation.
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Daolin Wei
    Associate Chief Physician, MD

    Former Associate Chief Physician in the Hematology Department at Shanghai First People's Hospital, he graduated from Fudan University Medical School, where he earned his doctoral degree. He completed his postdoctoral training at the University of Pittsburgh in the United States. With nearly 20 years of clinical and experimental research experience in hematology, he has participated in numerous multicenter clinical research projects, gaining extensive experience in clinical trial research and management. He has published over 10 papers in prestigious domestic and international journals, including one in an SCI-indexed journal.

    Expertise:
  • Diagnosis and treatment of refractory lymphoma and multiple myeloma
  • Therapies such as CAR-T, autologous, and allogeneic hematopoietic stem cell transplantation
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Ying Jiang
    Associate Chief Physician, MD

    Former Attending Physician in the Hematology Department at Shanghai First People's Hospital, he graduated from Shanghai Jiao Tong University School of Medicine, where he earned his doctoral degree. In 2014, he was a visiting scholar at the Immunology Laboratory of the Mayo Clinic in the United States. He has participated in several projects funded by the Shanghai Science and Technology Committee and the National Natural Science Foundation. His primary research achievements include individualized MRD monitoring and treatment post-hematopoietic stem cell transplantation and immunotherapy for hematologic malignancies.

    Expertise:
  • Diagnosis and treatment of malignant hematologic diseases
  • Research in lymphoma immunotherapy
  • Responsible for CAR-T therapy and management, as well as bridge-to-transplant treatment strategies.
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Su Li
    Attending Physician, MD

    Former Attending Physician in the Hematology Department at Shanghai First People's Hospital, with 10 years of professional experience in diagnosing and treating hematological diseases. His clinical research focuses on the diagnosis and treatment of pulmonary complications in patients undergoing hematopoietic stem cell transplantation.

    Expertise:
  • Diagnosis and treatment of various hematological diseases
  • Diagnosis and treatment of pulmonary infections in post-transplant patients
  • Treatment of refractory multiple myeloma and transplantation.
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Huixia Liu
    Attending Physician, MD

    Former Attending Physician in the Hematology Department at Shanghai First People's Hospital, with over 10 years of professional experience in diagnosing and treating hematological diseases. He has published six articles in renowned professional journals, including one in an SCI-indexed journal and five in core journals.

    Expertise:
  • Diagnosis and treatment of bone marrow failure diseases and myeloproliferative neoplasms
  • Hematopoietic stem cell transplantation, including autologous, allogeneic, and umbilical cord blood transplantation
  • Specializes in the treatment and transplantation for myelofibrosis
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Fucaso® (Equecabtagene Autoleucel Injection)

-- The World's First Approved Fully Human CAR-T Therapy

Breakthrough fully human CAR structure
  • Full epitope of light and heavy chains binds tightly to BCMA
  • Fast dissociation, low exhaustion
  • Low immunogenicity
Durable persistence
  • Median duration of persistence time 419 days
  • 12-month sustained MRD negativity rate 81.7%
  • 12-month PFS rate 85.5%
Strong efficacy
  • ORR 98.9%
  • ≥CR rate 82.4%
  • MRD negativity rate 97.8%
Returning to life upon single-dose treatment
Excellent safety
  • No ≥ Grade 3 ICANS
  • Incidence of ≥ Grade 3
  • No movement/cognitive disorder observed No Parkinson's disease found